Atracurium Dose Calculator

Clinical context

Atracurium is an intermediate-acting nondepolarizing neuromuscular blocker. It produces paralysis without sedation, analgesia, or amnesia. Administer only to an adequately anesthetized or sedated patient when ventilation, airway management, and resuscitation are immediately available. The calculator returns a user-selected IV bolus. Onset and duration vary with dose, age, temperature, acid-base status, interacting drugs, and neuromuscular disease. Larger or rapidly administered doses can cause histamine-mediated hypotension, flushing, tachycardia, or bronchospasm. Patients with myasthenia gravis or other neuromuscular disorders may have marked sensitivity. Use quantitative neuromuscular monitoring to guide repeat dosing and recovery. Confirm adequate recovery before extubation. Atracurium may be antagonized with an acetylcholinesterase inhibitor when spontaneous recovery is present; sugammadex does not reverse atracurium.